One-day intensified lansoprazole-quadruple therapy for cure of Helicobacter pylori infection
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چکیده
منابع مشابه
One-day intensified lansoprazole-quadruple therapy for cure of Helicobacter pylori infection.
BACKGROUND Peptic ulcer patients need to be treated with antimicrobials to cure Helicobacter pylori infection. Seven-day quadruple therapy is the regimen with the highest cure rates. An ultra-short quadruple therapy was evaluated prospectively. METHODS Forty-six consecutive H. pylori positive patients (33 had proven ulcer disease) were prescribed lansoprazole 30 mg b.d. on days 1-4, and on da...
متن کاملOne-day quadruple therapy compared with 7-day triple therapy for Helicobacter pylori infection.
BACKGROUND Eradication of Helicobacter pylori infection has had an impact on the treatment and recurrence rates of peptic ulcer disease and malignancies such as mucosa-associated lymphoid tissue lymphoma. Treatment options are cumbersome, expensive, and associated with side effects. METHODS Randomized, prospective, open-labeled equivalence trial with a parallel-group design to compare eradica...
متن کاملThree-day lansoprazole quadruple therapy for Helicobacter pylori-positive duodenal ulcers: a randomized controlled study.
AIM To compare the efficacy and tolerability of a 3-day quadruple therapy with a standard 7-day triple therapy in eradicating Helicobacter pylori infection and healing duodenal ulcers. METHODS Patients with H. pylori-positive duodenal ulcers were randomized to receive either lansoprazole 30 mg, clarithromycin 500 mg, and metronidazole 400 mg twice daily for 7 days (LCM-7) or lansoprazole 30 m...
متن کامل1-day quadruple therapy was not inferior to 7-day triple therapy for eradication of Helicobacter pylori infection in dyspepsia.
P a t i e n t s 160 patients ≥ 18 years of age (mean age 50 y, 57% women) with dyspepsia and H. pylori infection who had a Glasgow Dyspepsia Severity Score (GDSS) of ≥ 3 (score range 0 to 20) and a positive carbon 14 urea breath test result. Exclusion criteria included previous treatment of H. pylori infection, pregnancy, personal or family history of gastrointestinal malignancy, antibiotic the...
متن کاملComparison of four-day and seven-day pantoprazole-based quadruple therapy as a routine treatment for Helicobacter pylori infection.
BACKGROUND H. pylori eradication is usually performed with three or four drugs for at least seven days. Recently four reports have shown a cure rate of approximately 90% using a four-day quadruple therapy. The objectives of this prospective study were: 1) to evaluate the efficacy of pantoprazole-based quadruple therapy, and 2) to compare the efficacy and tolerability of four-day with seven-day ...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology and Therapeutics
سال: 1997
ISSN: 0269-2813,1365-2036
DOI: 10.1046/j.1365-2036.1997.121292000.x